Recent News

We’re thrilled to share the preprint of our article titled “Single-cell analysis of pediatric acute myeloid leukemia samples uncovers treatment-resistant stem and mast cells” on bioRxiv. Check it out at https://www.biorxiv.org/content/10.1101/2024.07.09.602801 Big thanks to Denis Ohlstrom for leading the effort and performing excellent analysis in collaboration with other lab members and collaborators: Mojtaba Bakhtiary, Hope Mumme, Marina Michaud, Frank Chien, William Pilcher, Sarthak Satpathy, Sean Jordan, and Swati Bhasin! This article describes the largest single-cell RNA sequencing analysis of pediatric […]

Our article titled “Medulloblastoma Spatial Transcriptomics Reveals Tumor Microenvironment Heterogeneity with High-Density Progenitor Cell Regions Correlating with High-Risk Disease” is now online at bioRxiv! Here is the link: https://www.biorxiv.org/content/10.1101/2024.06.25.600684v1.   Huge thanks to Franlin Chien, Marina Michaud, and Mojtaba Bakhtiari for leading this analysis!

We are excited to announce that our paper titled “Early Injury Landscape in Vein Harvest by Single-Cell and Spatial Transcriptomics” has been published in Circulation Research! Go check it out at https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.123.323939!   Huge thanks to Marina Michaud, Mojtaba Bakhtiari, Beena Thomas, and William Pilcher for leading this effort!

Congratulations to Marina Michaud and Denis Ohlstrom, who received awards at the  2024 Atlanta Workshop for Single-Cell Omics (AWSOM)! Marina Michaud received the award for best oral presentation for her work titled “Integrated single-nuclei and spatial transcriptomic approach reveals acute endothelial injury during vein grafting procedures validated by RNAScope”, and Denis Ohlstrom received the award for the best poster presentation for his work titled “Single cell meta-analysis of 168 pediatric acute myeloid leukemia samples uncovers treatment resistant stem and mast cells”.