Sean Jordan

July 26, 2023

Marina Gives Presentation at Vascular Research Initiatives Conference

Congratulations to Marina Michaud, who gave a stellar presentation of her vein graft spatial transcriptomics research at the Vascular Research Initiatives Conference today! This is the biggest vascular biology conference in the world! Lab Members Involved: Marina Michaud
July 26, 2023

The Bhasin Lab Welcomes Baby Zayn!

Yara Beyh recently gave birth to a beautiful baby boy named Zayn! This is the first baby to be born to a current student in the Bhasin Lab. Congratulations Yara!  
May 4, 2023

The ‘omics of obesity in B-cell acute lymphoblastic leukemia

The obesity pandemic currently affects more than 70 million Americans and more than 650 million individuals worldwide. In addition to increasing susceptibility to pathogenic infections (eg, SARS-CoV-2), obesity promotes the development of many cancer subtypes and increases mortality rates in most cases. We and others have demonstrated that, in the context of B-cell acute lymphoblastic leukemia (B-ALL), adipocytes promote multidrug chemoresistance. Furthermore, others have demonstrated that B-ALL...
March 27, 2023

Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis

As part of the Multiple Myeloma Research Foundation (MMRF) immune atlas pilot project, we compared immune cells of multiple myeloma bone marrow samples from 18 patients assessed by single-cell RNA sequencing (scRNA-seq), mass cytometry (CyTOF), and cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) to understand the concordance of measurements among single-cell techniques. Cell type abundances are relatively consistent across the three approaches, while variations are...