Sean Jordan – Page 2

December 9, 2025

Longitudinal profiling of tumor and immune compartments uncovers patterns of dysregulation and associations with response in multiple myeloma

Multiple myeloma (MM) is a malignancy of clonally expanded plasma cells shaped by complex interactions with the immune microenvironment. To investigate immune correlates of treatment response and disease progression, we conducted multi-omics profiling including CD138neg single-cell RNA sequencing of 243 bone marrow samples from 102 patients (631,226 cells) and CD138pos bulk RNA and whole-genome sequencing from 209 samples. In longitudinal analyses, interferon-γ signaling associated with markers...

April 28, 2025

Marina’s Talk Wins Best Oral Presentation Award at AWSOM 2025!

Congrats to Marina Michaud, whose presentation titled “Integrated Coding and Non-Coding Transcriptional Single-Cell Atlas of Multiple Myeloma: Unraveling the Effects of Myeloma Genotype on the Bone Marrow” won the award for best oral presentation at the 2025 Atlanta Workshop on Single-cell Omics! Way to go, Marina – your exemplary performance makes the lab proud! Looking forward to seeing even more great work from you.

April 28, 2025

Denis’s Poster Wins Best Poster Award at AWSOM 2025!

Congrats to Denis Ohlstrom, whose presentation titled “Longitudinal characterization of multiple myeloma and the immune microenvironment” won the award for best poster presentation at the 2025 Atlanta Workshop on Single-cell Omics! Way to go Denis – you’re making the lab proud!

October 9, 2024

DFUCare: deep learning platform for diabetic foot ulcer detection, analysis, and monitoring

INTRODUCTION: Diabetic foot ulcers (DFUs) are a severe complication among diabetic patients, often leading to amputation or even death. Early detection of infection and ischemia is essential for improving healing outcomes, but current diagnostic methods are invasive, time-consuming, and costly. There is a need for non-invasive, efficient, and affordable solutions in diabetic foot care.